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Initially 10mg once daily; may increase to 20mg once daily after 1 week Discover an innovative, new and effective way to treat debilitating depression. It is approved for the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), diabetic peripheral neuropathic pain (DPNP), fibromyalgia, and chronic musculoskeletal pain. *DILI or Duloxetine-Induced Liver Injury is discussed at length in Kang et al. The efficacy of Cymbalta has been established in 5 Phase 3 clinical trials. Explore REXULTI Safety & Prescribing Info, & Boxed Warning. Cymbalta For Pain, Anxiety & Other Uses. If Antidepressants Aren't Working, Contact Us. REXULTI® (brexpiprazole) Important Safety, Prescribing Info & Boxed Warning. Cymbalta (duloxetine) is a discerning serotonin and norepinephrine reuptake inhibitor specially intended for the therapy of misery and generalised stress and anxiety disorder.
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