Research Funded

2022-2023 Robert Davidson Fellowships

Each of the fellows are respirologists and will spend at least 75 percent of their time conducting research and the balance of their time seeing patients, as well as teaching and taking part in other work in their clinics and collaborating with specialists across the country.

Advancing research and developing more respiratory specialists to improve care, as well as expand access to care, for people living with pulmonary fibrosis (PF) are the aims of CPFF’s investment in clinical research fellowships. This year’s four fellowship recipients are sure to have an impact on both expanding our knowledge of PF and further developing their clinical skills to best serve those with the disease.

Congratulations to the 2022-2023 CPFF Robert Davidson Fellows.

DR. ALEC CAMPBELL

DR. ALEC CAMPBELL
DR. AMANDA GRANT-ORSER
DR. AMANDA GRANT-ORSER
DR. BOHYUNG MIN

Working with Drs. Charlene Fell and Kerri Johannson, Dr. Min will care for patients at the University of Calgary (U of C) ILD clinic. She will also pursue an MSc in clinical epidemiology at U of C.

Her primary research study will investigate the relationship between the complete blood count (CBC) test and progression of fibrosing ILD to clarify its potential role as a simple and effective biomarker. This may help identify individuals who are at higher risk of disease progression and who may benefit from early treatment, close surveillance, or further diagnostic investigation.

DR. BOHYUNG MIN
DR. LEIGH MINUK
DR. LEIGH MINUK

Drs. Shane Shapera and Jolene Fisher at University Health Network (UHN), Toronto, will guide and mentor Dr. Leigh Minuk as she undertakes clinical work at Toronto General Hospital’s ILD clinic and her ILD research. Dr. Minuk will also pursue an MSc in clinical epidemiology at McMaster University.

Her main research study involves the development of a “staging” system to identify fibrosing ILD patients at high risk for disease progression and/or mortality. Such a system will help guide both therapy decisions such as when to begin anti-fibrotic medication and/or lung transplantation assessment, as well as, patient counselling.

2021-2022 Fellowship & Research Grant Recipients

DR. KELLY SUN

Under the supervision of Dr. Shane Shapera at the University of Toronto (U of T), Dr. Sun will care for patients at the Toronto General Hospital ILD clinic. She will also pursue a Master of Science degree, with a concentration in healthcare research and clinical epidemiology at U of T. Her main research proposal will delve into the management of patients with progressive fibrosing ILD (PF-ILD). She will be linking data from the Canadian Registry of Pulmonary Fibrosis (CARE-PF) with data from the Institute of Clinical and Evaluative Sciences (ICES) to validate a health administrative definition of PF-ILD. ICES analyzes data gathered through the routine administration of Ontario’s publicly funded healthcare system. In addition, the study will investigate issues regarding health care utilization, including related hospitalizations and estimated health care costs associated with ILD.

DR. KELLY SUN
DR. DANIEL MARINESCU
DR. DANIEL MARINESCU

Under the supervision of Dr. Chris Ryerson at UBC, Dr. Marinescu will move into his second-year as a CPFF fellow, and continue performing his 20 percent of clinical duties at St. Paul’s Hospital in Vancouver.  While pursuing his Master’s in Health Science at UBC, he will be involved in several research studies. His primary project is creating about 1,300 detailed clinical, radiological and histopathological findings across various ILD subtypes in the CARE-PF database. Eventually this rich data will be analyzed for associations with identified genetic risk factors for fibrotic ILD. The work will serve to better understand the biologic basis for ILD, helping to improve diagnosis and inform effective disease management. For more information about Dr. Marinescu’s research to date, please read the article in the June 2021 issue of Hope Breathes Here.

2020-2021 Fellowship & Research Grant Recipients

DR. COLIN ADAMS

Dr. Colin Adams will fulfill his fellowship clinical work at the ILD clinic at Toronto General Hospital. His primary project will be a Canadian Registry for Pulmonary Fibrosis (CARE-PF) study to develop a new prognostic score for all fibrotic ILD in conjunction with Dr. Jolene Fisher and Dr. Chris Ryerson at UBC. He will also contribute to the Multidisciplinary Interstitial Lung Disease Discussion with Experts Remotely (MILDDER) project, which provides an excellent opportunity for community outreach and facilitate quicker access to care for those living outside the Toronto area.

You can read about the results of Dr. Adams projects in the May 2021 issue of our newsletter.

DR. COLIN ADAMS
DR. AMANDA GRANT-ORSER
DR. AMANDA GRANT-ORSER

Dr. Amanda Grant-Orser will treat patients at the University of Calgary’s ILD Clinic located at South Health Campus as part of her fellowship. She will also pursue a Masters in Clinical Epidemiology. Her primary research project during her fellowship will focus on exploring how supplemental oxygen may improve pulmonary exercise hemodynamics in patients with fibrotic ILD and exertional hypoxemia. The ultimate goal of this work is to improve the quality of life and outcomes in patients living with ILD.

DR. SARAH MACISSAC

Dr. Sarah MacIsaac will be dedicating 25 percent of her fellowship time providing care to patients at the Firestone Institute for Respiratory Health (FIRH), McMaster University, in Hamilton. Her research time will include the completion of a Master’s degree in Public Health, as well as several research projects. Her key research project will be to evaluate the impact of anti-fibrotic treatment on the risk of acute exacerbation following definitive surgical resection or targeted radiation therapy for the management of lung cancer. She’ll also be conducting a quality improvement project to explore measures to expedite access to IPF specialists as well as reduce the interval between the decision to treat and patient receipt of anti-fibrotic therapy.

DR. SARAH MACISAAC
DR. DANIEL MARINESCU
DR. DANIEL MARINESCU

Dr. Daniel Marinescu will perform the clinical duties of his fellowship at St. Paul’s Hospital in Vancouver. While pursuing his Master’s in Health Science at UBC, he will be involved in several research studies. His primary project will examine the association of genetic risk factors with detailed radiological and histopathological findings across various ILD subtypes. The work will serve to better understand the biologic basis for ILD, potentially helping to improve diagnosis and inform effective disease management.

DR. CIARAN SCALLAN

Dr. Ciaran Scallan at the Firestone Institute for Respiratory Health in Hamilton, Ontario, was awarded $20,000 to to study the feasibility of using a sputum (phlegm) guided approach to treat chronic cough in PF patients using inhaled corticosteroids and azithromycin (a macrolide antibiotic) during a 12-week period. You can read more about this project in the December 2020 issue of our newsletter.

DR CIARAN SCALLAN
DR LEE FIDLER
DR. LEE FIDLER

Dr. Lee Fidler of Sunnybrook Health Sciences Centre in Toronto was awarded $20,000 to investigate the incidence and prevalence of rheumatoid arthritis interstitial lung disease (RA-ILD) in Ontario. You can read more about this research in the June 2022 issue of our newsletter.